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A. Vítex agnus castus

  1. Committee on Herbal Medicinal Products (2010) "Final Community herbal monograph on Vitex agnus-castus L., fructus". EMA. London: Doc. Ref.: EMA/HMPC/606742/2017.
    https://www.ema.europa.eu/en/documents/herbal-monograph/final-community-herbal-monograph-vitex-agnus-castus-l-fructus_en.pdf 
    [Consulta: 2020]
  2. Propiedades saludables de la Vitex agnus castus. https://registerofquestions.efsa.europa.eu/roqFrontend/login?0
  3. Agencia española de seguridad alimentaria y nutrición. AESAN. Registro de Ginevitex como complemento alimenticio. https://rgsa-web-aesan.mscbs.es/rgsa/formulario_principal_js.jsp
  4. Daniele, C., Thompson Coon, J., Pittler, M. H., & Ernst, E. (2005). "Vitex agnus castus: a systematic review of adverse events". Drug safety, 28(4), 319–332.
    https://doi.org/10.2165/00002018-200528040-00004
    [Consulta: 2020]
  5. COBOS GONZÁLEZ, I. Vitex agnus-castus y Desórdenes Femeninos
    https://www.fitoterapia.net/archivos/201306/vitex.pdf?1
    [Consulta: 2020]
  6. ROMM, A., CLARE, B., STANSBURY, J., RYAN, L., TRICKEY, R., LEE, L., HYWOOD, A. (2010). “Chapter 5: Menstrual Welness and Menstrual Problems” en Botanical medicine for women’s healt book, Churchill Livingstone.
    https://doi.org/10.1016/B978-0-443-07277-2.00007-6
  7. ROMM, A., BURGESS, I., WINSTRON, D., ZICK, S., MCQUADE CRAWFORD, A. (2010). “Chapter 7: Condicions of reproductive organs, Uterine fibroids” en Botanical medicine for women’s health book, Churchill Livingstone.
    https://doi.org/10.1016/B978-0-443-07277-2.00009-X
  8. HYWOOD, A., (2010). “Chapter 12: Fertility Challenges” en Botanical medicine for women’s health book, Churchill Livingstone.
    https://doi.org/10.1016/B978-0-443-07277-2.00014-3
  9. HOOBS, C,. (2003). “Vitex: The Women Herb”. Summertown, TN: Book Publishing Company.
  10. UNIVERSITAT DE LES ILLES BALEARS, DEPARTAMENT DE BIOLOGIA, ÀREA BOTÀNICA. Vítex agnus-castus L.
    http://herbarivirtual.uib.es/ca/general/469/especie/vitex-agnus-castus-l-
    [Consulta: 2020]
  11. WIKIPEDIA. Adaptógeno.
    https://es.wikipedia.org/wiki/Adapt%C3%B3geno
    [Consulta: 18-11-2020]
  12. https://www.fitoterapia.net/archivos/201306/vitex.pdf?1
  13. PLAZA, L., PUJADAS SALVÀ, A.J. Flora Vascular.
    https://www.floravascular.com/index.php?genero=Vitex
    [Consulta: 18-11-2020]

B. Estudios de evidencia de Vitex agnus castus

  1. VERKAIK, S., KAMPERMAN, A.M., VAN WESTRHENEN, R., SCHULTE, PFJ. (2017) “The treatment of premenstrual syndrome with preparations of Vitex agnus castus: a systematic review and meta-analysis” en Am J Obstet Gynecol. 217(2):150-166.
    doi:10.1016/j.ajog.2017.02.028
  2. CARMICHAEL, A.R., (2008) "Can Vitex Agnus castus Be Used for the Treatment of Mastalgia? What Is the Current Evidence?", Evidence-Based Complementary and Alternative Medicine, vol. 5, Article ID 651379, 4 pages.
    https://doi.org/10.1093/ecam/nem074
  3. CERQUEIRA, RO., FREY, BN., LECLERC, E., BRIETZKE, E. (2017) “Vitex agnus castus for premenstrual syndrome and premenstrual dysphoric disorder: a systematic review”. Arch Womens Ment Health. 20(6):713-719.
    doi:10.1007/s00737-017-0791-0
  4. AKSOY, AN., GÖZÜKARA, I., KABIL KUCUR, S. (2014) “Evaluation of the efficacy of Fructus agni casti in women with severe primary dysmenorrhea: a prospective comparative Doppler study”. J Obstet Gynaecol Res. 40(3):779-784.
    doi:10.1111/jog.12221
  5. ATMACA, M., KUMRU, S., TEZCAN, E. (2003). “Fluoxetine versus Vitex agnus castus extract in the treatment of premenstrual dysphoric disorder”. Hum Psychopharmacol. 18(3):191-195.
    doi:10.1002/hup.470
  6. RAFIEIAN-KOPAEI, M., MOVAHEDI, M. (2017) “Systematic Review of Premenstrual, Postmenstrual and Infertility Disorders of Vitex Agnus Castus”. Electron Physician. 9(1):3685-3689.
    doi:10.19082/3685
  7. NASERI, R., FARNIA, V., YAZDCHI, K., ALIKHANI, M., BASANJ, B., SALEMI, S. (2019). “Comparison of Vitex agnus-castus Extracts with Placebo in Reducing Menopausal Symptoms: A Randomized Double-Blind Study”. Korean J Fam Med. 40(6):362-367.
    doi:10.4082/kjfm.18.0067
  8. ARENTZ, S., ABBOTT, JA., SMITH, CA., BENSOUSSAN, A. (2014). “Herbal medicine for the management of polycystic ovary syndrome (PCOS) and associated oligo/amenorrhoea and hyperandrogenism; a review of the laboratory evidence for effects with corroborative clinical findings”. BMC Complement Altern Med.14:511.
    doi:10.1186/1472-6882-14-511
  9. ŠOŠIĆ-JURJEVIĆ, B., AJDŽANOVIĆ, V., FILIPOVIĆ, B., et al. (2016) “Functional morphology of pituitary -thyroid and -adrenocortical axes in middle-aged male rats treated with Vitex agnus castus essential oil”. Acta Histochem. 118(7):736-745.
    doi:10.1016/j.acthis.2016.07.007
  10. AHANGARPOUR, A., OROOJAN, AA., KHORSANDI, L., NAJIMI, SA. (2017) “Pancreatic protective and hypoglycemic effects of Vitex agnus-castus L. fruit hydroalcoholic extract in D-galactose-induced aging mouse model”. Res Pharm Sci. 2017;12(2):137-143.
    doi:10.4103/1735-5362.202452
  11. LAURITZEN, C., REUTER, HD., REPGES, R., BÖHNERT, KJ., SCHMIDT, U. (1997) “Treatment of premenstrual tension syndrome with Vitex agnus castus controlled, double-blind study versus pyridoxine”. Phytomedicine. 1997;4(3):183-189.
    doi:10.1016/S0944-7113(97)80066-9
  12. CAPPELLI, V., MORGANTE, G., DI SABATINO, A., MASSARO, MG., DE LEO, V. (2015). “Valutazione dell'efficacia di un nuovo preparato nutraceutico nel trattamento dei disturbi delle donne in postmenopausal [Evaluation of the efficacy of a new nutraceutical product in the treatment of postmenopausal symptoms]”. Minerva Ginecol. 2015;67(6):515-521.
    https://pubmed.ncbi.nlm.nih.gov/26788874/
  13. YAVARIKIA, P., SHAHNAZI, M., HADAVAND MIRZAIE, S., JAVADZEDEH, Y., LUTFI, R. (2013). “Comparing the effect of mefenamic Acid and vitex agnus on intrauterine device induced bleeding”. J Caring Sci. 2013;2(3):245-254. Published 2013 Aug 31.
    doi:10.5681/jcs.2013.030
  14. EFTEKHARI, MH., ROSTAMI, ZH., EMAMI, MJ., TABATABAEE, HR. (2014). “Eftekhari MH, Rostami ZH, Emami MJ, Tabatabaee HR. Effects of "vitex agnus castus" extract and magnesium supplementation, alone and in combination, on osteogenic and angiogenic factors and fracture healing in women with long bone fracture”. J Res Med Sci. 2014;19(1):1-7.
    PMC3963316
  15. AMBROSINI, A., DI LORENZO, C., COPPOLA, G., PIERELLI, F. (2013) “Use of Vitex agnus-castus in migrainous women with premenstrual syndrome: an open-label clinical observation”. Acta Neurol Belg. 2013;113(1):25-29.
    doi:10.1007/s13760-012-0111-4
  16. LEE, H., JUNG, KH., LEE, H., PARK, S., CHOI, W., BAE, H. (2015) “Casticin, an active compound isolated from Vitex Fructus, ameliorates the cigarette smoke-induced acute lung inflammatory response in a murine model”. Int Immunopharmacol. 2015;28(2):1097-1101.
    doi:10.1016/j.intimp.2015.07.041
  17. SONG, XL., ZHANG, YJ., WANG, XF., et al. (2017) “Casticin induces apoptosis and G0/G1 cell cycle arrest in gallbladder cancer cells”. Cancer Cell Int. 2017;17:9. Published 2017 Jan 5.
    doi:10.1186/s12935-016-0377-3
  18. ROSA, SI., RIOS-SANTOS, F., BALOGUN, SO., MARTINS, DT. (2016) “Vitexin reduces neutrophil migration to inflammatory focus by down-regulating pro-inflammatory mediators via inhibition of p38, ERK1/2 and JNK pathway”. Phytomedicine. 2016;23(1):9-17.
    doi:10.1016/j.phymed.2015.11.003
  19. WEBSTER, DE., LU, J., CHEN, SN., FARNSWORTH, NR., WANG, ZJ., (2006). “Activation of the mu-opiate receptor by Vitex agnus-castus methanol extracts: implication for its use in PMS”. J Ethnopharmacol. 2006;106(2):216-221.
    doi:10.1016/j.jep.2005.12.025
  20. MILEWICZ, A., GEJDEL, E., SWOREN, H., et al (1993). “Vitex agnus castus-Extrakt zur Behandlung von Regeltempoanomalien infolge latenter Hyperprolaktinämie. Ergebnisse einer randomisierten Plazebo-kontrollierten Doppelblindstudie” [Vitex agnus castus extract in the treatment of luteal phase defects due to latent hyperprolactinemia. Results of a randomized placebo-controlled double-blind study]. Arzneimittelforschung. 1993;43(7):752-756.
    https://pubmed.ncbi.nlm.nih.gov/8369008/
  21. IRIBARNE-DURÁN, L.M., DOMINGO-PIÑAR, S., PEINADO, FM., VELA-SORIA, F., JIMÉNEZ-DÍAZ, I., BARRANCO, E., OLEA, N., FREIRE, C., ARTACHO-CORDÓN, F., OCÓN-HERNÁNDEZ, O. (2020). “Menstrual blood concentrations of parabens and benzophenones and related factors in a sample of Spanish women: An exploratory study” Environmental Research. 2020, Volume 183, 109228, ISSN 0013-9351
    https://doi.org/10.1016/j.envres.2020.109228.
  22. VAN DIE, M. D., BURGER, H. G., TEEDE, H. J., & BONE, K. M. (2009). Vitex agnus-castus (Chaste-Tree/Berry) in the treatment of menopause-related complaints. Journal of alternative and complementary medicine (New York, N.Y.)15(8), 853–862. https://doi.org/10.1089/acm.2008.0447

C. Alteradores hormonales (disruptores endocrinos)

  1. FUNDACIÓN ALBORADA. Enfermedades ambientales - Sistema endocrino.
    https://www.fundacion-alborada.org/enfermedades-ambientales/sistema-endocrino-2/
    [Consulta: 18-11-2020]
  2. RECUPERA TU CICLO. Desequilibrios hormonales más comunes (no culpes a tus hormonas).
    https://recuperatuciclo.com/desequilibrios-hormonales-mas-comunes/
    [Consulta: 18-11-2020]
  3. ECOLOGISTAS EN ACCIÓN. Directo a tus hormonas: Guía de alimentos disruptores. Residuos de plaguicidas con capacidad de alterar el sistema endocrino en los alimentos españoles.
    https://www.ecologistasenaccion.org/wp-content/uploads/2020/07/informe-directo-a-tus-hormonas-2020.pdf
    [Consulta: 18-11-2020]
  4. THE ENDOCRINE DISRUPTION EXCHANGE. TEDX list of potential endocrine disruptors - search de tedx list.
    https://endocrinedisruption.org/interactive-tools/tedx-list-of-potential-endocrine-disruptors/search-the-tedx-list
    [Consulta: 18-11-2020]
  5. MINISTERIO DE TRABAJO, MIGRACIONES Y SEGURIDAD SOCIAL. Bases de datos de sustancias tóxicas y peligrosas RISCTOX.
    https://risctox.istas.net/index.asp?idpagina=610
    [Consulta: 18-11-2020]
  6. COMISIÓN EUROPEA. Comunicación de la comisión al Parlamento Europeo, al Consejo, al Comité Económico y Social Europeo y al Comité de las Regiones. Hacia un marco de la Unión Europea más exhaustivo en materia de alteradores endocrinos.
    https://ec.europa.eu/transparency/regdoc/rep/1/2018/ES/COM-2018-734-F1-ES-MAIN-PART-1.PDF
    [Consulta: 18-11-2020]
  7. FUNDACIÓN ALBORADA. Que no te alteren las hormonas.
    https://www.fundacion-alborada.org/areas/proyectos-2/que-no-te-alteren-las-hormonas/
    [Consulta: 18-11-2020]
  8. INSTITUTO NACIONAL PARA LA SEGURIDAD Y LA SALUD OCUPACIONAL. La seguridad reproductiva y el lugar de trabajo.
    https://www.cdc.gov/spanish/niosh/topics/reprod/reprodfemalehazard.html
    [Consulta: 18-11-2020]

D. Libros / Revistas

  1. Hablemos de vaginas. Salud Femenina desde una perspectiva global. Miriam Al Adib Mendiri. Ed. Oberon.
  2. MyS Mujeres y Salud. Revista de Comunicación Interactiva.
  3. Revista Gansos Salvajes. www.gansossalvajes.com
  4. Manual introductorio a la Ginecología Natural, Pabla Pérez San Martín.
  5. Revista Cuerpo Mente. Extra Salud. Plantas que curan
  6. Vitex, the Women´s Herb. Christopher Hobbs, L.Ac. BPC Healthy Living Publications
  7. Encyclopedia of Dietary Supplements: //books.google.es/books?id=Sfmc-fRCj10C&pg=PA95&lpg=PA95&dq=vitex+rosacea&source=bl&ots=lPIF-ClAGH&sig=ACfU3U1euzLRBQ0akiPIsDkZsh9c3gLmEQ&hl=es&sa=X&ved=2ahUKEwjg2Zbj–blAhVLxYUKHdr_BQoQ6AEwCHoECAkQAQ#v=onepage&q=vitex%20rosacea&f=false
  8. Cuerpo de Mujer, Sabiduría de Mujer: Una guia para la salud física y emocional. Christiane Northrup. Ed. Urano
  9. Vicente, Macías, de la Fuente, González, Montero & Catalá-López, 2013.
  10. Regla sin dolor. Anna Huete, Ed. Oceano Ambar
  11. Botanical Medicine for Women's health ebook. CHAPTER 5 – Menstrual Wellness and Menstrual Problems. Aviva Romm, Bevin Clare, Jill E Stansbury, Linda Ryan, Ruth Trickey, Laurel Lee, Angela J. Hywood. CHAPTER 7 -Conditions of reproductive organs. Uterine fibroids. Aviva Romm, Isla Burgess, David Winston, Suzanna M. Zick, Amanda McQuade Crawford . CHAPTER 12- Fertility Challenges Angela J. Hywood.
  12. STENGLER, M. (2013). Los tratamientos curativos de los médicos naturistas. Ediciones Obelisco
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